2011年的最后一期NEJM!12月29日365卷第26期的这期新鲜NEJM,颇为给力!你绝对不能错过!

【原始论文】

1. 高危患者髋关节术后的自由或限制性输血

Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery

[评论] 聚焦输血阈值

Transfusion Thresholds in FOCUS

2. 低分子肝素和危重患者的死亡率

Low-Molecular-Weight Heparin and Mortality in Acutely Ill Medical Patients

3. 贝伐单抗对卵巢癌的首次治疗

Incorporation of Bevacizumab in the Primary Treatment of Ovarian Cancer

4. 贝伐单抗治疗卵巢癌的3期试验 

A Phase 3 Trial of Bevacizumab in Ovarian Cancer

5. **慢性淋巴细胞白血病的_SF3B1_和其他新的癌基因**

SF3B1 and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia

[评论] 癌症中的RNA剪接机制的突变

Mutations in RNA Splicing Machinery in Human Cancers

6. 简报:3例完整面部移植的患者

Three Patients with Full Facial Transplantation

【综述】

发病机制:在健康与疾病中的前蛋白转化酶

Mechanisms of Disease: Proprotein Convertases in Health and Disease

【MGH病例报道】

52岁男性出现乏力、感染与肾上腺增大

A 52-Year-Old Man with Weakness, Infections, and Enlarged Adrenal Glands

【基础研究的临床意义】

糖尿病干细胞的“移动病”

Diabetic Stem-Cell “Mobilopathy”

【观察】

1. 临床的版权与开放获取

Copyright and Open Access at the Bedside(免费全文)

2. 少有人走的路

The Road Less Traveled

【临床图片】

1. A Head Shot (免费全文)

2. Lichtenberg Figures(免费全文)

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